Oximes as potential inhibitors glucose transfer in prostate cancer cells

Project leader: Ivana Vrhovac Madunić

Project participants: Maja Katalinić, Josip Madunić, Dean Karaica, Antonio Zandona, Ana-Marija Lulić

Croatian Academy of Sciences and Arts

Duration: 2021-2022


The aim of this project is to determine whether newly synthesized oxime compounds inhibit glucose uptake and thus the growth of human prostate cancer cells and as such can be considered as candidates for antitumor drugs. Most of the newly synthesized oximes that will be examined are either constantly positively charged quaternary amines, or contain amino groups that could be strongly protonated under physiological conditions.