Nevenka Kopjar

Division of Toxicology

PhD / Permanent Scientific Advisor

Place and date of birth

Varaždin (Croatia), 1969

Education

  • Faculty of Science, University of Zagreb (1987-1992)
  • Postgraduate study (Biology), Faculty of Science, University of Zagreb (1993-2000)

Work Experience

  • University of Zagreb, Faculty of Science, Department of Biology, Division of Zoology (1992-1997)
  • Institute for Medical Research and Occupational Health, Mutagenesis Unit (since 1997)

Fields of interest

genetic toxicology; cytogenetics; biomonitoring; studying the effects of physical and chemical mutagens in vitro and in vivo; science editing

Select Publications

    1. Jakac M, Brčić Karačonji I, Jurič A, LuÅ”ić D, Milinčić D, Dramićanin A, PeÅ”ić M, Landeka N, Kopjar N. Preliminary Insights into the Cyto/Genoprotective Properties of Propolis and Its Constituent Galangin In Vitro. Toxics. 2025 Mar 8;13(3):194. doi: 10.3390/toxics13030194.
    2. RaÅ”ić D, Zandona A, Katalinić M, ČeÅ”i M, Kopjar N. Assessing the Potential Synergistic/Antagonistic Effects of Citrinin and Cannabidiol on SH-SY5Y, HepG2, HEK293 Cell Lines, and Human Lymphocytes. Toxins (Basel). 2024;16(12):534. doi: 10.3390/toxins16120534.
    3. Kopjar N, Fuchs N, Brčić Karačonji I, Žunec S, Katić A, Kozina G, Lucić Vrdoljak A. High Doses of Ī”9-Tetrahydrocannabinol Might Impair Irinotecan Chemotherapy: A Review of Potentially Harmful Interactions. Clinical Drug Investigation. 2020;40(9):775-787. doi: 10.1007/s40261-020-00954-y.
    4. Kopjar N, Fuchs N, Žunec S, Mikolić A, Micek V, Kozina G, Lucić Vrdoljak A, Brčić Karačonji I. DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Ī”9-Tetrahydrocannabinol. Molecules. 2019;24(8):1560. doi: 10.3390/molecules24081560.
    5. Kopjar N, Žunec S, MendaÅ” G, Micek V, KaÅ”uba V, Mikolić A, Lovaković BT, Milić M, Pavičić I, Čermak AMM, Pizent A, Lucić Vrdoljak A, Želježić D. Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA damage in blood and brain tissue of adult male Wistar rats. Chemico-Biological Interactions. 2018;279:51-63. doi: 10.1016/j.cbi.2017.10.029.
    6. Lucić Vrdoljak A, Žunec S, Radić B, Fuchs R, Želježić D, Kopjar N. Evaluation of the cyto/genotoxicity profile of oxime K048 using human peripheral blood lymphocytes: an introductory study. Toxicology In Vitro. 2014 Feb;28(1):39-45. doi: 10.1016/j.tiv.2013.06.007.
    7. Kopjar N, KaÅ”uba V, Rozgaj R, Želježić D, Milić M, Ramić S, Pavlica V, Milković-Kraus S.Ā The genotoxic risk in health care workers occupationally exposed to cytotoxic drugs – A comprehensive evaluation by the SCE assay. Journal of Environmental Science and Health – Part A Toxic/Hazardous Substances and Environmental Engineering 2009;44(5):462-479.
    8. Kopjar N, Želježić D, Lucić Vrdoljak A, Radić B, Ramić S, Milić M, Gamulin M, Pavlica V, Fučić A. Irinotecan toxicity to human blood cells in vitro: Relationship between various biomarkers. Basic & Clinical Pharmacology & Toxicology 2007;100(6):403-413.
    9. Kopjar N, Garaj-Vrhovac, V.Ā Application of the alkaline comet assay in human biomonitoring for genotoxicity: a study on Croatian medical personnel handling antineoplastic drugs. Mutagenesis 2001; 16(1):71-78.

List of publications