Anita Bosak

Zagreb, January 1974

• 2005–2010 Faculty of Science, University of Zagreb. “Inhibition of cholinesterases by catechol and resorcinol derivatives” [Doctoral thesis]. Supervisor: Z. Kovarik.
• 2000–2004 Faculty of Science, University of Zagreb. “Interaction of cholinesterases with enantiomers of quinuclidin-3-ol derivatives” [M. Sc. Thesis]. Supervisor: Vera Simeon.
• 1992–1998 Faculty of Science, University of Zagreb; Diploma in Chemistry. “Michaelis constants and maximum reaction rates for the hydrolysis of phenylacetate by human serum arylesterases” [B.Sc. Thesis]. Supervisor: E. Reiner.

• Since 1999 Institute for Medical Research and Occupational Health, Zagreb, Croatia

• biochemistry,
• enzyme kinetic,
• interaction of cholinesterases with reversible and progressive inhibitors,
• stereoselectivity of cholinesterases towards enantiomers of pharmacologically active compounds

• September 2003 “8th International Summer School on Biophysics, Supramolecular Structure and Function“, Rovinj, Croatia
• September 2006 “Molecular Design and Computer Assisted Combinatorial Chemistry“, ICS-UNIDO Trieste, Italy
• October 2007 Laboratory for Molecular Neurobiology, Medical Faculty, Ljubljana, Slovenia
• November 2011 “Biochemistry and Molecular Biology Education Workshop“, Ljubljana, Slovenia
• September 2013 Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia
• October 2014 “Scientific Publishing and Intellectual Property Protection in the Life Sciences”, Zagreb, Croatia
• May 2015 Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia
• October 2015 “The Application of the 3R Approach in Working with Laboratory Animals“, Zagreb, Croatia
• December 2016 “Basics of Proteomics“, Zagreb, Croatia

• 2009 Annual award for young scientist in 2008- The Croatian Society of Biochemistry and Molecular Biology
• 2009 Annual award of the Institute for Medical Research and Occupational Health for young researchers in 2008
• 2012 Annual award of the Institute for Medical Research and Occupational Health for the publication with the highest number of citations
• 2013 Annual award of the Institute for Medical Research and Occupational Health for the scientific paper published in 2002. in a journal best rated according to JCR Science Edition

1. P. Eyer, F. Worek, D. Kiderlen, G. Sinko, A. Stuglin, V. Simeon-Rudolf, E. Reiner, Molar absorption coefficients for the reduced Ellman reagent: reassessment, Analytical Biochemistry 312 (2003) 224–227.
2. A. Bosak, I. Primožič, M. Oršulić, S. Tomić, V. Simeon-Rudolf, Enantiomers of quinuclidin-3-ol derivatives: Resolution and interactions with human cholinesterases, Croatica Chemica Acta 78 (2005) 121-128.
3. I. Gazić, A. Bosak, G. Šinko, V. Vinković, Z. Kovarik, Preparative HPLC separation and stereoselective inhibition of human cholinesterases, Analytical and Bioanalytical Chemistry 385 (2006) 1513-1519.
4. A. Bosak, I. Gazić, V. Vinković, Z. Kovarik, Stereoselective inhibition of cholinesterases by bambuterol enantiomers, Chemico-Biological Interactions 175 (2008) 192-195.
5. A. Bosak, I. Gazić-Smilović, G. Šinko, V. Vinković, Z. Kovarik, Metaproterenol, Isoproterenol, and their bisdimethylcarbamate derivatives as human cholinesterase inhibitors, Journal of Medicinal Chemistry 55 (2012) 6716-6723.
6. M. Katalinić, A. Bosak, Z. Kovarik, Flavonoids as inhibitors of human butyrylcholinesterase variants, Food Technology and Biotechnology 52(1) (2014) 64-67.

• The Croatian Biochemical Society
• The Croatian Toxicological Society
• The Croatian Society of Natural Sciences (treasurer since 2016)