Radiobiology

Programme:

Ionizing radiation. Interaction of radiation with matter. Biological effects of radiation on molecular, cellular, tissue and body level (early and late effects). Repair processes. Chemical modificators (radioprotectors and radiosensibilisators). Dosimetry. Radioactive isotopes. Non-ionizing radiations and their use in biological investigations and biomedicine. Exercises: instruments and detectors for ionizing radiation. Assessment of the radiation effects on hematopoesis processes in experimental animals (blood smears, experimental bone marrow transplantation). The application of radioactive isotopes in biological investigations. The application of cytogenetic techniques in detection of genome damage induced by ionizing radiation (analysis of chromosomal aberrations, micronucleus assay and the alkaline comet assay).

Literature:

  1. Nias A.H.W. (1998):
    An introduction to radiobiology, John Willey and Sons. Ltd.
  2. Polk C., Postow E. (1996):
    Biological Effects of Electromagnetic Fields, CRC Press
  3. Hitchock T., Patterson R.M. (1995):
    Radiofrequency and ELF Electromagnetic Energies, International Thompson Publishing Inc.
  4. Tubiana M, Dutreix J, Wambersie A, Bewley D. (1990):
    Introduction to radiobiology, Taylor and Francis.
  5. Kiefer (1990):
    Biological radiation effects, Springer Verlag.
  6. IAEA (1986):
    Biological dosimetry – Chromosomal aberration analysis for dose assessment, Atomic Energy Tech Report Series 260.